Hyalinizing Trabecular Adenoma of Thyroid : A Rare Case Report
نویسندگان
چکیده
Introduction: Hyalinizing trabecular tumor (HTT) is an unusual thyroid neoplasm that was first described by Carney in 1987.Many cytological and histological features of such tumors may be mistaken for Papillary Thyroid Carcinoma (PTC) and Medullary Thyroid Carcinoma (MTC).This can lead to overtreatment like total thyroidectomy and lymph node dissection. Here, we present a rare case of hyalinizing trabecular tumor of thyroid in a young female emphasizing the pathological features of HTT, which may help to reduce over diagnosis thereby guiding proper management. Case report: A 40 year old female patient presented with a lump in the left side of the neck. Lump increased gradually over a period of 5 months and was associated with mild pain and restricted neck movement. Thyroid profile of the patient was within normal limits. USG revealed a solid cold nodule, which was regarded as a thyroid adenoma. Nodule was surgically removed and after pathological examination diagnosed as hyalinizing trabecular adenoma (HTA) of thyroid. Conclusion: Hyalinizing trabecular adenoma is rare and can be confused with malignant lesions of thyroid. Some peculiar histomorphological features mentioned in this case report will help in diagnosis and further management.
منابع مشابه
[Trabecular hyalinizing adenoma of the thyroid (HAT): A report of two cases].
The hyalinizing trabecular adenoma is a rare lesion of the thyroid. There is controversy in the literature about the correct name for this disease. Dr. Carney defended the benign nature of this condition and therefore continues calling it adenoma, the World Health Organization calls for the potential of tumor malignancy, and others qualify it as a variant of papillary carcinoma based on the pre...
متن کاملHyalinizing trabecular tumor of the thyroid: Case report and review of the literature.
In 1987, Carney et al described a rare thyroid tumor termed hyalinizing trabecular adenoma presenting characteristics consisting of a trabecular growth pattern and hyalinizing stroma. In subsequent reports, the observed nuclear features and RET alterations led this tumor to be linked to papillary carcinoma. Subsequent reports concerning hyalinizing trabecular carcinoma further complicated its c...
متن کاملMedico-historical overview and histopathological comments about a hyalinizing trabecular tumor case of thyroid gland.
INTRODUCTION Hyalinizing Trabecular Tumor (HTT) of the thyroid gland is a rare and controversial tumor, whose rigorous identification is extremely important due to the difficulty of establishing a correct diagnosis using only the routine histological stains (Hematoxylin-Eosin, Periodic Acid-Schiff, van Gieson, etc.). Using only usual stains, difficult problems of differential diagnosis arise. I...
متن کاملHyalinizing trabecular tumor masquerading as papillary thyroid carcinoma on fine-needle aspiration.
BACKGROUND/AIMS Hyalinizing trabecular tumors are rare neoplasms of the thyroid gland often mistaken for thyroid carcinoma on fine-needle aspiration. We review the distinguishing characteristics of hyalinizing trabecular tumors and their management. METHODS We present the case of a patient diagnosed with papillary thyroid carcinoma on fine-needle aspiration as well as a review of the literatu...
متن کامل[Hyalinizing trabecular adenoma of the thyroid].
Hyalinizing trabecular adenoma (HTA) is a follicle-derived tumor of the thyroid gland that has been described recently. The differential diagnosis includes medullar carcinoma, papillary carcinoma, and paraganglioma of the thyroid. We report a case of thyroid HTA in a 25-year-old woman. The tumor appeared as a <> of the left thyroid in radionuclide scans. Histologically, the tumor s...
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تاریخ انتشار 2015